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Sildenafil is a powerful and selective inhibitor of cGMP-unique phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP within the corpus cavernosum. The molecular structure of sildenafil is analogous to that of cGMP and acts as a competitive binding agent of PDE5 within the corpus cavernosum, resulting in far more cGMP and in

If a dosage works properly but results in bothersome Unwanted side effects, your health care provider may suggest a decrease dosage. If a dosage doesn’t work that will help you get or preserve an erection, your physician might increase your dosage.COVID-19 could cause endothelial problems, which could add to erectile dysfunction. Neurological res